Basic Information
| LncRNA/CircRNA Name | GHET1 |
| Synonyms | GHET1, lncRNA-GHET1 |
| Region | GRCh38_7:148987527-148989432 |
| Ensemble | ENSG00000281189 |
| Refseq | NR_130107 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, western blot etc. |
| Sample | breast cancer tissues, cell lines (SKBR3, ZR-75- 681, BT-20 and MCF-7) |
| Expression Pattern | up-regulated |
| Function Description | Our results demonstrated that GHET1 was up-regulated in breast cancer tissues and cell lines, and promoted breast cancer cell proliferation, invasion and migration by affecting EMT. |
| Pubmed ID | 29843220 |
| Year | 2018 |
| Title | Long non-coding RNA GHET1 promotes human breast cancer cell proliferation, invasion and migration via affecting epithelial mesenchymal transition |
External Links
| Links for GHET1 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |