Basic Information
| LncRNA/CircRNA Name | GAS5-AS1 |
| Synonyms | NA |
| Region | GRCh38_1:173863248-173863941 |
| Ensemble | ENSG00000270084 |
| Refseq | NR_037605 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qRT-qPCR, Western blot |
| Sample | glioma tissues,cell lines (U251, U87MG, U373, and LN229) |
| Expression Pattern | up-regulated |
| Function Description | lncRNA?GAS5-AS1?inhibited glioma proliferation, migration, and invasion by sponging miR-106b-5p and regulating the expression of TUSC2 |
| Pubmed ID | 32072565 |
| Year | 2020 |
| Title | LncRNA GAS5-AS1 inhibits glioma proliferation, migration, and?invasion via miR-106b-5p/TUSC2 axis |
External Links
| Links for GAS5-AS1 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |