Basic Information
| LncRNA/CircRNA Name | GAS5 |
| Synonyms | GAS5, NCRNA00030, SNHG2, ENST00000456293.5, GAS5-007 |
| Region | GRCh38_1:173863900-173868882 |
| Ensemble | ENSG00000234741 |
| Refseq | NR_002578 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | melanoma |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | melanoma tissues, cell lines (A2058, B16, M21, MM200, MEL-RM and A375) |
| Expression Pattern | down-regulated |
| Function Description | the expression of GAS5 was down-regulated in melanoma tissues compared to adjacent normal tissues. Finally, we suggested that GAS5 inhibited the growth of melanoma through miR-137 in vivo. |
| Pubmed ID | 28386376 |
| Year | 2017 |
| Title | Long non-coding RNA GAS5 inhibits tumorigenesis via miR-137 in melanoma |
External Links
| Links for GAS5 | GenBank HGNC NONCODE |
| Links for melanoma | OMIM COSMIC |