Basic Information
LncRNA/CircRNA Name | GAS5 |
Synonyms | GAS5, NCRNA00030, SNHG2, ENST00000456293.5, GAS5-007 |
Region | GRCh38_1:173863900-173868882 |
Ensemble | ENSG00000234741 |
Refseq | NR_002578 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | bladder cancer |
ICD-0-3 | C67 |
Methods | Microarray, qPCR etc. |
Sample | bladder cancer tissues |
Expression Pattern | down-regulated |
Function Description | In the training set, uc004cox.4 was up-regulated and GAS5 was down-regulated in BC patients. Moreover, the expression of urinary uc004cox.5 was an independent predictor for the recurrence of NMIBC patients. |
Pubmed ID | 29516641 |
Year | 2018 |
Title | Cell-free lncRNA expression signatures in urine serve as novel non-invasive biomarkers for diagnosis and recurrence prediction of bladder cancer. |
External Links
Links for GAS5 | GenBank HGNC NONCODE |
Links for bladder cancer | OMIM COSMIC |