Basic Information
LncRNA/CircRNA Name | GAS5 |
Synonyms | NA |
Region | GRCh38_1:173863900-173868882 |
Ensemble | ENSG00000234741 |
Refseq | NR_002578 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | Breast Cancer |
ICD-0-3 | C50 |
Methods | qPCR, Western blot |
Sample | MCF-7 cell line, MDA-MB231 cell line |
Expression Pattern | differential expression |
Function Description | Our results indicated that some of the lncRNAs having tumor suppressor (GAS5, MEG3, lincRNA-p21) and oncogenic roles (HOTAIR) are regulated by c-MYC. |
Pubmed ID | 31326549 |
Year | 2019 |
Title | MYC-Driven Regulation of Long Non-Coding RNA profiles in Breast Cancer Cells |
External Links
Links for GAS5 | GenBank HGNC NONCODE |
Links for Breast Cancer | OMIM COSMIC |