Basic Information
| LncRNA/CircRNA Name | GAS5 |
| Synonyms | GAS5, NCRNA00030, SNHG2, ENST00000456293.5, GAS5-007 |
| Region | GRCh38_1:173863900-173868882 |
| Ensemble | ENSG00000234741 |
| Refseq | NR_002578 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, other |
| Sample | blood |
| Expression Pattern | NA |
| Function Description | Genetic polymorphism of GAS5 may influence the development of gastriccancer and so could be a new marker of this disease. The link with disease may involve p27Kip1 expression. |
| Pubmed ID | 30269656 |
| Year | 2019 |
| Title | A Functional Genetic Variant in GAS5 lncRNA (rs145204276) Modulates p27 Kip1 Expression and Confers Risk for Gastric Cancer |
External Links
| Links for GAS5 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |