Basic Information
| LncRNA/CircRNA Name | GAS5 |
| Synonyms | NA |
| Region | GRCh38_1:173863900-173868882 |
| Ensemble | ENSG00000234741 |
| Refseq | NR_002578 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Luciferase reporter assay, RNAi, Western blot, Microarray, RIP |
| Sample | lung cancer tissues, cell lines(A549, H460, 95D, H1299, SPC-A-1, H522,16-HBE) |
| Expression Pattern | up-regulated |
| Function Description | Upregulation of Long Noncoding RNA GAS5 Inhibits Lung Cancer Cell Proliferation and Metastasis via miR-205/PTEN Axis. |
| Pubmed ID | 30926767 |
| Year | 2019 |
| Title | Upregulation of Long Noncoding RNA GAS5 Inhibits Lung Cancer Cell Proliferation and Metastasis via miR-205/PTEN Axis. |
External Links
| Links for GAS5 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |