Basic Information
| LncRNA/CircRNA Name | AGAP2-AS1 |
| Synonyms | NA |
| Region | GRCh38_12:57726271-57728356 |
| Ensemble | ENSG00000255737 |
| Refseq | NR_027032 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, RNA-seq |
| Sample | PC tissues,cell lines (BxPC-3, SW1990, PANC-1,AsPC-1) |
| Expression Pattern | up-regulated |
| Function Description | In summary, our data show that RREB1-induced upregulation of AGAP2-AS1 regulates cell proliferation and migration in PC partly through suppressing ANKRD1 and ANGPTL4 by recruiting EZH2. |
| Pubmed ID | 30814490 |
| Year | 2019 |
| Title | RREB1-induced upregulation of the lncRNA AGAP2-AS1 regulates the proliferation and migration of pancreatic cancer partly through suppressing ANKRD1 and ANGPTL4. |
External Links
| Links for AGAP2-AS1 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |