Basic Information
| LncRNA/CircRNA Name | GAPLINC |
| Synonyms | GAPLINC, LINC01540 |
| Region | GRCh38_18:3466250-3478978 |
| Ensemble | ENSG00000266835 |
| Refseq | NR_110429 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Western blot etc. |
| Sample | gastric cancer tissues, cell lines (KATO III, HGC-27, and SNU-1) |
| Expression Pattern | up-regulated |
| Function Description | The lncRNA GAPLINC expression was upregulated and positively correlated with MAPK1 expression in gastric cancer tissues and cells. lncRNA GAPLINC promotes gastric cancer cell proliferation by acting as a molecular sponge of miR-378 to modulate MAPK1 expression. |
| Pubmed ID | 29785127 |
| Year | 2018 |
| Title | Long noncoding RNA GAPLINC promotes gastric cancer cell proliferation by acting as a molecular sponge of miR-378 to modulate MAPK1 expression |
External Links
| Links for GAPLINC | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |