Basic Information
| LncRNA/CircRNA Name | GACAT3 |
| Synonyms | GACAT3, LINC01458, lncRNA-AC130712 |
| Region | GRCh38_2:16050427-16085801 |
| Ensemble | ENSG00000236289 |
| Refseq | NR_126559 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot, Luciferase reporting assay etc. |
| Sample | cell lines (A549, H157,HCC827, H838), NSCLC tissue |
| Expression Pattern | up-regulated |
| Function Description | Overexpression of ectopic GACAT3 in A549 cells promoted cell proliferation and migration, and enhanced the sensitivity of lung cancer cells to radiotherapy. |
| Pubmed ID | 29565489 |
| Year | 2018 |
| Title | High expression of lncRNA GACAT3 inhibits invasion and metastasis of non-small cell lung cancer to enhance the effect of radiotherapy. |
External Links
| Links for GACAT3 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |