Basic Information
| LncRNA/CircRNA Name | AB073614 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | RT-qPCR, Western blot analysis |
| Sample | GC tissues,cell lines (SGC-7901, BGC-823, HGC-27,GES) |
| Expression Pattern | up-regulated |
| Function Description | AB073614 expression level in GC samples was significantly higher than that of adjacent ones. Besides, the migration and invasion of GC cells were obviously repressed after AB073614 was knocked down. After AB073614 was knocked down in vitro, the mRNA and protein expressions of insulin-like growth factor 2 (IGF-2) was remarkably down-regulated. |
| Pubmed ID | 31957827 |
| Year | 2020 |
| Title | Long Non-Coding RNA AB073614 Promotes Metastasis of Gastric Cancer Cells by Upregulating IGF-2 |
External Links
| Links for AB073614 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |