Basic Information
| LncRNA/CircRNA Name | FOXCUT |
| Synonyms | FOXCUT, LINC01379, TCONS_00011636 |
| Region | GRCh38_6:1605531-1606079 |
| Ensemble | ENSG00000280916 |
| Refseq | NR_125804 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | oral squamous cell carcinoma |
| ICD-0-3 | C06.9 |
| Methods | qPCR, RNAi, Western blot etc. |
| Sample | OSCC tissues, cell lines (Tca8113, OSC-4, SCC1 etc.) |
| Expression Pattern | up-regulated |
| Function Description | In this study, we report a new lncRNA FOXC1 upstream transcript (FOXCUT) that was remarkably overexpressed in 23 OSCC patients, as was the adjacent FOXC1 gene. The expressions of FOXC1 and FOXCUT were positively correlated. In conclusion, FOXC1 may be co-amplified with FOXCUT in OSCC, and both of them may be functionally involved in the tumor progression of OSCC. |
| Pubmed ID | 24889262 |
| Year | 2014 |
| Title | The expression and functional role of a FOXC1 related mRNA-lncRNA pair in oral squamous cell carcinoma. |
External Links
| Links for FOXCUT | GenBank HGNC NONCODE |
| Links for oral squamous cell carcinoma | OMIM COSMIC |