Basic Information
| LncRNA/CircRNA Name | FLVCR1-AS1 |
| Synonyms | NA |
| Region | GRCh38_1:212852108-212858088 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Luciferase reporter assay, Western blot |
| Sample | GC tissues and 3 GC cell lines |
| Expression Pattern | up-regulated |
| Function Description | High expression of FLVCR1-AS1 correlated with poor clinical outcomes and prognosis in patients with GC. FLVCR1-AS1 promoted proliferation and invasion of GC cells by acting as a ceRNA to sponge miR-155. |
| Pubmed ID | 30899380 |
| Year | 2019 |
| Title | Long non-coding RNA FLVCR1-AS1 sponges miR-155 to promote the tumorigenesis of gastric cancer by targeting c-Myc. |
External Links
| Links for FLVCR1-AS1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |