Basic Information
| LncRNA/CircRNA Name | FLJ33360 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Western blot, Luciferase reporter assay etc |
| Sample | HCC tissues, cell lines (Hep3B, Huh7, SMMC-7221, MHCC88H, Bel-7402 and HepG2) |
| Expression Pattern | up-regulated |
| Function Description | FLJ33360 was upregulated in HCC tissues relative to paracancerous ones. After knockdown of FLJ33360, migratory and invasive capacities in Bel-7402 and HepG2 cells were attenuated. There were five miRNA candidates predicted to bind FLJ33360, and miRNA-140 was the most differentially expressed by FLJ33360 regulation. |
| Pubmed ID | 32194906 |
| Year | 2020 |
| Title | LncRNA FLJ33360 Accelerates the Metastasis in Hepatocellular Carcinoma by Targeting miRNA-140/MMP9 Axis |
External Links
| Links for FLJ33360 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |