Basic Information
| LncRNA/CircRNA Name | FLANC |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qRT-PCR, Western blot |
| Sample | CRC tissue,cell lines |
| Expression Pattern | up-regulated |
| Function Description | Flanc as a novel primate- specific lncrna that is highly upregulated in crc cells and regulates metastases formation. Targeting primate- specific transcripts such as Flanc may represent a novel and low toxic therapeutic strategy for the treatment of patients. |
| Pubmed ID | 31988194 |
| Year | 2020 |
| Title | Therapeutic potential of FLANC, a novel primate-specific long non- coding RNA in colorectal?cancer |
External Links
| Links for FLANC | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |