Basic Information
| LncRNA/CircRNA Name | FER1L4 |
| Synonyms | FER1L4, C20orf124 |
| Region | GRCh38_20:35558737-35607562 |
| Ensemble | ENSG00000088340 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal cancer |
| ICD-0-3 | C15 |
| Methods | qPCR |
| Sample | esophageal cancer tissue, cell lines (Eca109, EC9706, KYSE30, KYSE150, and KYSE450) |
| Expression Pattern | down-regulated |
| Function Description | Results of qRT-PCR showed that, compared with that in normal tissues, FER1L4 was lowly expressed in ESCC tissues. Overexpression of FER1L4 could inhibit cell proliferation and invasion, promote apoptosis and increase the cell cycle distribution in G0/G1 phase. |
| Pubmed ID | 29771417 |
| Year | 2018 |
| Title | LncRNA FER1L4 suppressed cancer cell growth and invasion in esophageal squamous cell carcinoma |
External Links
| Links for FER1L4 | GenBank HGNC NONCODE |
| Links for esophageal cancer | OMIM COSMIC |