Basic Information
| LncRNA/CircRNA Name | FENDRR |
| Synonyms | NA |
| Region | GRCh38_16:86474529-86509099 |
| Ensemble | ENSG00000268388 |
| Refseq | NR_033925 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR |
| Sample | CRC tissues,cell lines (HCT116, SW480 HT29, and LOVO) |
| Expression Pattern | down-regulated |
| Function Description | lncRNA FENDRR is downregulated in CRC and negatively correlated with advanced stage and poor clinical outcomes of patient with CRC.FENDRR exerts an inhibitory role in CRC by interacting with miR-18a-5p and future increases ING4 expression. |
| Pubmed ID | 31724220 |
| Year | 2019 |
| Title | Long non-coding RNA FENDRR restrains the aggressiveness of CRC via regulating miR-18a-5p/ING4 axis |
External Links
| Links for FENDRR | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |