Basic Information
| LncRNA/CircRNA Name | EWSAT1 |
| Synonyms | EWSAT1, LINC00277, NCRNA00277, TMEM84 |
| Region | GRCh38_15:69072926-69095820 |
| Ensemble | ENSG00000212766 |
| Refseq | NR_026949 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | Western blot etc. |
| Sample | Primary ovarian tumor tissues, ovarian cancer cell lines (SKOV-3, HO8910, HO8910PM, ES2) |
| Expression Pattern | up-regulated |
| Function Description | In our study, we found the expression of EWSAT1 was upregulated in ovarian cancer cell lines and samples. Ecoptic expression of EWSAT1 suppressed miR-330-5p expression in ovarian cancer cell. In addition, the expression of miR-330-5p was downregulated in ovarian cancer cell lines and samples. |
| Pubmed ID | 28979684 |
| Year | 2017 |
| Title | LncRNA EWSAT1 promotes ovarian cancer progression through targeting miR-330-5p expression. |
External Links
| Links for EWSAT1 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |