Basic Information
| LncRNA/CircRNA Name | AFAP1-AS1 |
| Synonyms | AFAP1-AS1, AFAP1-AS, AFAP1AS, LOC84740 |
| Region | GRCh38_4:7754090-7778928 |
| Ensemble | ENSG00000272620 |
| Refseq | NR_026892 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | nasopharyngeal cancer |
| ICD-0-3 | C11 |
| Methods | qPCR etc. |
| Sample | cell lines (6-10B, 5-8F, CNE1, CNE2 and B95-9) |
| Expression Pattern | down-regulated |
| Function Description | A profile of three circulating lncRNAs (MALAT1, AFAP1-AS1 and AL359063) was established for NPC diagnosis. By Receiver Operating Characteristic (ROC) curve analysis, this three-lncRNA signature showed high accuracy in discriminating NPC from healthy control. |
| Pubmed ID | 28467811 |
| Year | 2017 |
| Title | Serum long non-coding RNAs MALAT1, AFAP1-AS1 and AL359063 as diagnostic and prognostic biomarkers for nasopharyngeal carcinoma. |
External Links
| Links for AFAP1-AS1 | GenBank HGNC NONCODE |
| Links for nasopharyngeal cancer | OMIM COSMIC |