Basic Information
| LncRNA/CircRNA Name | ENST00000563280 |
| Synonyms | FOXC2-AS1, ODRUL |
| Region | GRCh38_16:86565145-86567761 |
| Ensemble | ENSG00000260944 |
| Refseq | NR_125795 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | doxorubicin | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR, MTT assay etc. |
| Sample | cell line (MG63/DXR) |
| Expression Pattern | up-regulated |
| Function Description | The results showed that lncRNA ENST00000563280, uc021pbg.1, ENST00000568031, ENST00000545508, uc010lgv.1, ENST00000553559 and uc003txt.3 were up-regulated and that NR-036444, ENST00000440570, ENST00000476909, NR_040001, ENST00000457390, uc002sts.4, ENST00000576810 and ENST00000565617 were down-regulated in the doxorubicin-resistant MG63/DXR cells compared with their parental MG63 cell controls. |
| Pubmed ID | 26464619 |
| Year | 2015 |
| Title | Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis. |
External Links
| Links for ENST00000563280 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |