Basic Information
| LncRNA/CircRNA Name | ENST00000559981 |
| Synonyms | PLEKHH1 |
| Region | GRCh38_14:67533301-67589612 |
| Ensemble | ENSG00000054690 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR etc. |
| Sample | glioblastoma tissues |
| Expression Pattern | up-regulated |
| Function Description | In our expression profling analysis, the lncRNA ENST00000520186, ENST00000559981, ENST00000547415 and ENST00000518554 were separately considered as the ceRNA of miR-15a, miR-21, miR-29b and miR-29c in GBM. So far, these ceRNAs have not been reported implicated in GBM. Four mRNAs may be regulated by these miRNAs and lncRNAs, the PPP3CA have been reported to be aberrantly expressed in other tumors, but have not been studied in GBM. |
| Pubmed ID | 27600337 |
| Year | 2016 |
| Title | Identification and functional characterization of lncRNAs acting as ceRNA involved in the malignant progression of glioblastoma multiforme. |
External Links
| Links for ENST00000559981 | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |