Basic Information
| LncRNA/CircRNA Name | ENST00000512916 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ameloblastoma |
| ICD-0-3 | NA |
| Methods | RT-qPCR, Western blot, Microarray |
| Sample | AB tissues |
| Expression Pattern | up-regulated |
| Function Description | LncRNA ENST00000512916 was up-regulated in AB tissues . ENST00000512916 knockdown significantly inhibited cell proliferation , migration and the expression of CDK2/4/6 in AM-1 cells.ENST00000512916 overexpression significantly promoted the expression of HOXC13 in AM-1 cells. Overexpression of ENST00000512916 promoted cell cycle progression in AM-1 cells, which was reversed by HOXC13 knockdown. |
| Pubmed ID | 32110049 |
| Year | 2020 |
| Title | A Novel lncRNA ENST00000512916 Facilitates Cell Proliferation, Migration and Cell Cycle Progression in Ameloblastoma |
External Links
| Links for ENST00000512916 | GenBank HGNC NONCODE |
| Links for ameloblastoma | OMIM COSMIC |