Basic Information
| LncRNA/CircRNA Name | ENST00000480032 |
| Synonyms | SCN2A, BFIC3, BFIS3, BFNIS, EIEE11, HBA, HBSCI, HBSCII, NAC2, Na(v)1.2, Nav1.2, SCN2A1, SCN2A2 |
| Region | GRCh38_2:165194993-165392310 |
| Ensemble | ENSG00000136531 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma multiforme |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR etc. |
| Sample | GBM tissues |
| Expression Pattern | down-regulated |
| Function Description | The expressions of ENST00000559148 and n410783 lncRNAs were up-regulated; the levels of CDC20, CDC25C, CCNB2, and CDC45 mRNAs that were co-expressed with ENST00000559148 were increased; and the down-regulated ARRB1, PTPN5, MAPK8IP3, and PAK1 mRNAs and the up-regulated CDK4 mRNA were co-expressed with n410783. The expression levels of eight mRNAs that were co-expressed with two down-regulated lncRNAs (ENST00000532691 and ENST00000480032) in GBM were lower than those in normal brain tissues. |
| Pubmed ID | 27604987 |
| Year | 2016 |
| Title | LncRNA and mRNA expression profiles of glioblastoma multiforme (GBM) reveal the potential roles of lncRNAs in GBM pathogenesis. |
External Links
| Links for ENST00000480032 | GenBank HGNC NONCODE |
| Links for glioblastoma multiforme | OMIM COSMIC |