Basic Information
| LncRNA/CircRNA Name | ENST00000462717 |
| Synonyms | PSMD6-AS1, lnc00462717 |
| Region | GRCh38_3:64011964-64016246 |
| Ensemble | ENSG00000243410 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | papillary thyroid cancer |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR etc. |
| Sample | blood |
| Expression Pattern | up-regulated |
| Function Description | Compared with 131I-avid lung metastases, we discovered that two lncRNAs (ENST00000462717 and ENST00000415582) were upregulated and two (TCONS_00024700 and NR_028494) were downregulated in the non-131I-avid lung metastases of PTC. Low (ENST00000462717 and ENST00000415582) and high plasma lncRNA levels (TCONS_00024700 and NR_028494) were also found to be associated with better prognosis of PTC patients with lung metastases. |
| Pubmed ID | 27997908 |
| Year | 2016 |
| Title | Circulating Long Non-Coding RNAs Act as Biomarkers for Predicting 131I Uptake and Mortality in Papillary Thyroid Cancer Patients with Lung Metastases. |
External Links
| Links for ENST00000462717 | GenBank HGNC NONCODE |
| Links for papillary thyroid cancer | OMIM COSMIC |