Basic Information
| LncRNA/CircRNA Name | ENST00000422494 |
| Synonyms | LINC01384, TCONS_00028337 |
| Region | GRCh38_20:22587522-22607517 |
| Ensemble | ENSG00000237396 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | papillary thyroid cancer |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR etc. |
| Sample | papillary thyroid carcinoma tissues |
| Expression Pattern | down-regulated |
| Function Description | We randomly chose a total of 10 differentially expressed lncRNAs for qPCR, of which TCONS_l2_00010365, n386477, n340790, lnc-LLPH-2:1 and NR_003225.2 were up-regulated and lnc-PSD4-1:14, n335550, lnc-KCMF1-2:1, lnc-PLA2R1-1:1 and ENST00000422494.1 were down-regulated in PTC. The results of qPCR were consistent with those of the microarray, in that all 10 lncRNAs were differentially expressed with the same trend (up- or down-regulated) and reached statistical significance. |
| Pubmed ID | 26003293 |
| Year | 2015 |
| Title | Genome-wide analysis of long noncoding RNA expression profile in papillary thyroid carcinoma. |
External Links
| Links for ENST00000422494 | GenBank HGNC NONCODE |
| Links for papillary thyroid cancer | OMIM COSMIC |