Basic Information
| LncRNA/CircRNA Name | ENST00000418077 |
| Synonyms | RPL23P11, RPL23_6_1032 |
| Region | GRCh38_10:33864313-33864723 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | Microarray, qPCR, Cell proliferation assay etc. |
| Sample | cell lines (PC9, H1975, H1299 and A549) |
| Expression Pattern | down-regulated |
| Function Description | Four upregulated and four downregulated lncRNAs from differentially expressed lncRNAs were randomly selected. Using RT-qPCR the results of microarray in PC9/R vs. PC9 were validated. The expression levels of ENST00000507437, ENST00000508827, NR_026685 and BC087858 were upregulated and ENST00000381279, ENST00000418077, BG188549 and BE244504 were downregulated. Thus, the microarray data were confirmed by RT-qPCR. |
| Pubmed ID | 25482516 |
| Year | 2015 |
| Title | Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancer. |
External Links
| Links for ENST00000418077 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |