Basic Information
| LncRNA/CircRNA Name | AFAP1-AS1 |
| Synonyms | NA |
| Region | GRCh38_4:7754090-7778928 |
| Ensemble | ENSG00000272620 |
| Refseq | NR_026892 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qRT-PCR etc. |
| Sample | tumor tissues and adjacent non-cancerous tissues |
| Expression Pattern | down-regulated |
| Function Description | AFAP1-AS1 were significantly downregulated in gastric tumor samples compared with ANCTs.Relative expressions of AFAP1-AS1 were associated with the location of primary tumor, in that AFAP1 and AFAP1-AS1 were significantly downregulated in all cardia tumor types compared with their paired ANCTs.Additionally, a lower expression level of AFAP1 was detected in younger patients and in high grade tumor types compared with olders and low grade tumors respectively and significantly higher expression levels of AFAP1-AS1 in patients with lymphatic/vascular invasion compared with those without lymphatic/vascular invasion. |
| Pubmed ID | 31086663 |
| Year | 2019 |
| Title | AFAP1 and Its Naturally Occurring Antisense RNA Are Downregulated in Gastric Cancer Samples |
External Links
| Links for AFAP1-AS1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |