Basic Information
| LncRNA/CircRNA Name | EGOT |
| Synonyms | NA |
| Region | GRCh38_3:4749192-4751590 |
| Ensemble | ENSG00000235947 |
| Refseq | NR_004428 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | RT-PCR, Western blot |
| Sample | HCC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | EGOT markedly regulated viability, migration and invasion of HCC cells. The expression level of EGOT was negatively correlated the expression level of miR-33a-5p. |
| Pubmed ID | 32021242 |
| Year | 2019 |
| Title | Long Non-Coding RNA EGOT Promotes the Malignant Phenotypes of Hepatocellular Carcinoma Cells and Increases the Expression of HMGA2 via Down-Regulating miR-33a-5p |
External Links
| Links for EGOT | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |