Basic Information
| LncRNA/CircRNA Name | EGFR-AS1 |
| Synonyms | NA |
| Region | GRCh38_7:55179750-55188934 |
| Ensemble | ENSG00000224057 |
| Refseq | NR_047551 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR, Western blot etc |
| Sample | BC tissue,cell line (HT-1197) |
| Expression Pattern | up-regulated |
| Function Description | It was revealed that epidermal growth factor receptor-antisense RNA 1 (EGFR-AS1) was upregulated in BC and positively associated with rho associated coiled-coil containing protein kinase 2 (ROCK2). Analysis of data collected in follow-ups indicated that EGFR-AS1 expression was significantly associated with poorer overall survival of patients with BC. |
| Pubmed ID | 32194685 |
| Year | 2020 |
| Title | Long Non-Coding RNA EGFR-AS1 Sponges micorRNA-381 to Upregulate ROCK2 in Bladder Cancer |
External Links
| Links for EGFR-AS1 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |