Basic Information
| LncRNA/CircRNA Name | EGFLAM-AS1 |
| Synonyms | EGFLAM-AS1 |
| Region | GRCh38_5:38425036-38427376 |
| Ensemble | ENSG00000249491 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, RNAi, Western blot etc. |
| Sample | gastric cancer tissues, cell lines (SGC-7901, AGS, BGC-823, HG-27, GES-1) |
| Expression Pattern | down-regulated |
| Function Description | Significantly reduced expression of lncRNA-LOWEG was found in gastric cancer tissues and cell lines (SGC-7901, AGS, BGC-823 and HG-27) compared with patient-matched nontumorous adjacent tissues or the normal gastric cell line GES-1. Lastly, western blot and real-time PCR analysis suggested that lncRNA-LOWEG is positively correlated with the expression of leukemia inhibitory factor receptor (LIFR) gene at the translational level. |
| Pubmed ID | 26537802 |
| Year | 2015 |
| Title | A novel long noncoding RNA-LOWEG is low expressed in gastric cancer and acts as a tumor suppressor by inhibiting cell invasion. |
External Links
| Links for EGFLAM-AS1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |