Basic Information
| LncRNA/CircRNA Name | E330013P06 |
| Synonyms | E33 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qRT-PCR, Western blot assay |
| Sample | Plasma samples,breast cancer cell lines (MDA-MB-231, T47D) |
| Expression Pattern | up-regulated |
| Function Description | Compared with breast cancer patients without diabetes, diabetic patients without breast cancer and healthy peoples, LncRNAE330013P06 was upregulated in breast cancer patient with diabetes. Furthermore, of 34 breast patients, high LncRNAE330013P06 expression was significantly associated with family history, tumor-node-metastasis stage and lymph node metastasis. E33 promoted cancer cell growth in vitro via downregulation of P53. |
| Pubmed ID | 31907990 |
| Year | 2020 |
| Title | Long Non-Coding RNAE330013P06 Promotes Progression of Breast Cancer With Type 2 Diabetes |
External Links
| Links for E330013P06 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |