Basic Information
| LncRNA/CircRNA Name | DUXAP8 |
| Synonyms | NA |
| Region | GRCh38_22:15784959-15829984 |
| Ensemble | ENSG00000206195 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal cancer |
| ICD-0-3 | C15 |
| Methods | qPCR, western blot |
| Sample | esophageal cancer tissue, cell lines (TE-1, ESCCA109, ESCCA9706 and KYSE520) |
| Expression Pattern | up-regulated |
| Function Description | DUXAP8 expression was significantly correlated with tumor stage, lymph node metastasis and poor prognosis of ESCC patients. DUXAP8 may promote the occurrence of ESCC via Wnt/B-catenin pathway. |
| Pubmed ID | 29771416 |
| Year | 2018 |
| Title | Long non-coding RNA DUXAP8 regulates proliferation and invasion of esophageal squamous cell cancer |
External Links
| Links for DUXAP8 | GenBank HGNC NONCODE |
| Links for esophageal cancer | OMIM COSMIC |