Basic Information
| LncRNA/CircRNA Name | DUXAP10 |
| Synonyms | PCAN-3 |
| Region | GRCh38_14:19294785-19337674 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR |
| Sample | cell lines (IOSE386,HEY, HO8910 and A2780) |
| Expression Pattern | up-regulated |
| Function Description | DUXAP10 was significantly overexpressed in ovarian cancer tissues,and its expression was positively correlated with tumor size and FIGO stage in clinical patients. DUXAP10 played a role in promoting the proliferation of ovarian cancer cells and was expected to be a predictor and a potential therapeutic target of ovarian cancer. The overall survival rate of DUXAP10 overexpressing ovarian cancer patients was significantly lower than that of DUXAP10 low expression group. |
| Pubmed ID | 29424918 |
| Year | 2018 |
| Title | Highly expressed long non-coding RNA DUXAP10 promotes proliferation of ovarian cancer. |
External Links
| Links for DUXAP10 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |