Basic Information
| LncRNA/CircRNA Name | DMTF1v4 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | qPCR, Western blot, etc. |
| Sample | colon cancer tissues, cell line (HT-29) |
| Expression Pattern | up-regulated |
| Function Description | lncRNA DMTF1v4 promotes colon cancer cell proliferation and migration, and inhibits apoptosis by downregulating the expression of p-ERK, p-JNK, and p-p38, thus affecting the progression of colon cancer. Compared with the control group, the cell survival rate in the DMTF1v4-siRNA group was significantly decreased. |
| Pubmed ID | 29949153 |
| Year | 2018 |
| Title | Study on the function and mechanism of long non-coding RNA DMTF1v4 in the occurrence of colon cancer. |
External Links
| Links for DMTF1v4 | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |