Basic Information
| LncRNA/CircRNA Name | DLX6-AS1 |
| Synonyms | DLX6-AS1, DLX6-AS, DLX6AS, Evf-2, NCRNA00212 |
| Region | GRCh38_7:96955141-97014065 |
| Ensemble | ENSG00000231764 |
| Refseq | NR_015448 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | qPCR, Western blot, RIP, Luciferase reporter assays etc. |
| Sample | renal cell carcinoma tumors, cell lines (A498, ACHN, Caki-1, Caki2, 786-O and G401) |
| Expression Pattern | up-regulated |
| Function Description | In this study, we identified an upregulated lncRNA, DLX6-AS1, in RCC tumor tissues compared with normal kidney tissues. Our data suggested that DLX6-AS1 promoted RCC cell growth and tumorigenesis via targeting miR-26a. |
| Pubmed ID | 28881158 |
| Year | 2017 |
| Title | Long noncoding RNA DLX6-AS1 promotes renal cell carcinoma progression via miR-26a/PTEN axis |
External Links
| Links for DLX6-AS1 | GenBank HGNC NONCODE |
| Links for renal cell carcinoma | OMIM COSMIC |