Basic Information
| LncRNA/CircRNA Name | DLX6-AS1 |
| Synonyms | NA |
| Region | GRCh38_7:96955141-97014065 |
| Ensemble | ENSG00000231764 |
| Refseq | NR_015448 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qRT-PCR, Western blot |
| Sample | BC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | DLX6-AS1 was overexpressed in BC tissues and cell lines. Functional experiments verified that the oncogenic role of DLX6-AS1 on BC cell proliferation and invasion was through modulating miR-505-3p/RUNX2 axis, which might provide a promising target for BC therapy. |
| Pubmed ID | 31705901 |
| Year | 2019 |
| Title | Long noncoding RNA DLX6-AS1 promotes breast cancer progression via miR-505-3p/RUNX2 axis |
External Links
| Links for DLX6-AS1 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |