Basic Information
| LncRNA/CircRNA Name | DLEU7-AS1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | ENSG00000237152 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blot |
| Sample | colorectal cancer tissues, cell lines (HCT-8, HT-29, HCT-116 and SW-620) |
| Expression Pattern | up-regulated |
| Function Description | The expression of DLEU7-AS1 is significantly increased in CRC, which is markedly associated with CRC staging, lymph node metastasis, distant metastasis and poor prognosis. DLEU7-AS1 may promote the proliferation, invasion and migration capacities of CRC through regulating the Wnt/B-catenin pathway.DLEU7-AS1 Expression was Correlated with Clinical Staging, Lymph Node Metastasis, Distant Metastasis and Overall Survival of CRC Patients |
| Pubmed ID | 29364477 |
| Year | 2018 |
| Title | Long non-coding RNA DLEU7-AS1 promotes the occurrence and development of colorectal cancer via Wnt/B-catenin pathway. |
External Links
| Links for DLEU7-AS1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |