Basic Information
| LncRNA/CircRNA Name | AFAP1-AS1 |
| Synonyms | NA |
| Region | GRCh38_4:7754090-7778928 |
| Ensemble | ENSG00000272620 |
| Refseq | NR_026892 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qRT-PCR, Western blot, RIP |
| Sample | GC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | LncRNA AFAP1-AS1 accelerates the proliferative and migratory abilities of GC cells by downregulating the expression of KLF2, thus promoting the progression of GC. |
| Pubmed ID | 32016968 |
| Year | 2020 |
| Title | Long non-coding RNA AFAP1-AS1 promotes proliferation and migration of gastric cancer by downregulating KLF2 |
External Links
| Links for AFAP1-AS1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |