Basic Information
LncRNA/CircRNA Name | AFAP1-AS1 |
Synonyms | NA |
Region | GRCh38_4:7754090-7778928 |
Ensemble | ENSG00000272620 |
Refseq | NR_026892 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | qRT-PCR |
Sample | GC tissues,cell lines |
Expression Pattern | up-regulated |
Function Description | AFAP1-AS1 might be an oncogenic lncRNA that promoted GC progression by acting as a competing endogenous RNA (ceRNA) that regulates the expression of FGF7 through sponging miR-155-5p, suggesting that AFAP1-AS1 may be a novel potential therapeutic target for GC. |
Pubmed ID | 32051698 |
Year | 2020 |
Title | Long Noncoding RNA AFAP1-AS1 Promotes Cell Proliferation and Metastasis via the miR-155-5p/FGF7 Axis and Predicts Poor Prognosis in Gastric Cancer |
External Links
Links for AFAP1-AS1 | GenBank HGNC NONCODE |
Links for gastric cancer | OMIM COSMIC |