Basic Information
| LncRNA/CircRNA Name | DGCR5 |
| Synonyms | DGCR5, LINC00037, NCRNA00037 |
| Region | GRCh38_22:18970514-18994628 |
| Ensemble | ENSG00000237517 |
| Refseq | NR_002733 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR etc. |
| Sample | serum, HCC tissues |
| Expression Pattern | down-regulated |
| Function Description | DGCR5 was found down-regulated in HCC tissues and serum and low expression of DGCR5 was correlated with a poor cancer specific survival, as the overall 5-year CSS rates were 10.3% (low expression group) and 36.6% (high expression group), respectively. |
| Pubmed ID | 27898409 |
| Year | 2016 |
| Title | Down-Regulation of LncRNA DGCR5 Correlates with Poor Prognosis in Hepatocellular Carcinoma. |
External Links
| Links for DGCR5 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |