Basic Information
| LncRNA/CircRNA Name | DGCR5 |
| Synonyms | NA |
| Region | GRCh38_22:18970514-18994628 |
| Ensemble | ENSG00000237517 |
| Refseq | NR_002733 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | hepatocellular carcinoma tissues,cell lines(Huh-7, HepG2) |
| Expression Pattern | up-regulated |
| Function Description | Propofol elevated DGCR5 expression in Huh-7 and HepG2 cells. Increased expression of DGCR5 was connected with the anticancer activity of propofol on Huh-7 and HepG2 cells. |
| Pubmed ID | 31538334 |
| Year | 2019 |
| Title | Propofol exerts anticancer activity on hepatocellular carcinoma cells by raising lncRNA DGCR5. |
External Links
| Links for DGCR5 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |