Basic Information
| LncRNA/CircRNA Name | DCST1-AS1 |
| Synonyms | NA |
| Region | GRCh38_1:155045191-155046118 |
| Ensemble | ENSG00000232093 |
| Refseq | NR_040772 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | doxorubicin and Paclitaxel. | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | triple negative breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Western blot, Luciferase reporter assay, RIP etc |
| Sample | TNBC tissues, cell lines (MDA-MB-231, BT-549, T-47D, and MCF7) |
| Expression Pattern | differential expressed |
| Function Description | DCST1-AS1 Affects TGF-?-Induced Vimentin and E-Cadherin Expression in TNBC Cells.DCST1-AS1 Promotes TGF-?-Induced Migration and Invasion in TNBC Cells. |
| Pubmed ID | 32226772 |
| Year | 2020 |
| Title | DCST1-AS1 Promotes TGF-?-Induced Epithelial-Mesenchymal Transition and Enhances Chemoresistance in Triple-Negative Breast Cancer Cells via ANXA1 |
External Links
| Links for DCST1-AS1 | GenBank HGNC NONCODE |
| Links for triple negative breast cancer | OMIM COSMIC |