Basic Information
| LncRNA/CircRNA Name | DANCR |
| Synonyms | DANCR, AGU2, ANCR, KIAA0114, SNHG13, lncRNA-ANCR |
| Region | GRCh38_4:52712404-52720351 |
| Ensemble | ENSG00000226950 |
| Refseq | NR_024031 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, RNAi, Western blot, Cell proliferation assay etc. |
| Sample | HCC tissues, cell lines (SMMC-7721 and HCCLM3) |
| Expression Pattern | up-regulated |
| Function Description | DANCR was up-regulated in tumor tissues and plasma of patients with HCC, and its expression was highly correlated with microvascular and liver capsule invasion of HCC. Furthermore, knockdown of DANCR repressed the B-catenin pathway and inhibited HCC cell proliferation and metastasis both in vitro and in vivo. |
| Pubmed ID | 27919960 |
| Year | 2016 |
| Title | DANCR Acts as a Diagnostic Biomarker and Promotes Tumor Growth and Metastasis in Hepatocellular Carcinoma. |
External Links
| Links for DANCR | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |