Basic Information
| LncRNA/CircRNA Name | DANCR |
| Synonyms | DANCR, AGU2, ANCR, KIAA0114, SNHG13, lncRNA-ANCR |
| Region | GRCh38_4:52712404-52720351 |
| Ensemble | ENSG00000226950 |
| Refseq | NR_024031 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | triple negative breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Western blot, RNAi, etc. |
| Sample | breast cancer cell lines (MCF-7, T47D, MDA-MB-468, MDA-MB-231), TNBC tissues |
| Expression Pattern | up-regulated |
| Function Description | In the present study, our results showed that DANCR expression was increased in TNBC tissues compared with the adjacent normal tissues using quantitative real-time PCR (qRT-PCR) in 63TNBC specimens. The correlation between lncRNA DANCR expression and the overall survival of TNBC patients. Kaplan-Meier analysis of overall survival was analyzed according to lncRNA DANCR expression levels. |
| Pubmed ID | 28760736 |
| Year | 2017 |
| Title | Targeting long non-coding RNA DANCR inhibits triple negative breast cancer progression. |
External Links
| Links for DANCR | GenBank HGNC NONCODE |
| Links for triple negative breast cancer | OMIM COSMIC |