Basic Information
| LncRNA/CircRNA Name | DANCR |
| Synonyms | NA |
| Region | GRCh38_4:52712404-52720351 |
| Ensemble | ENSG00000226950 |
| Refseq | NR_024031 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | qPCR, Western blot |
| Sample | cell lines (SW620, SW480, HCT116, HT29, HCT15, Caco-2) |
| Expression Pattern | up-regulated |
| Function Description | DANCR was revealed to be overexpressed in all human colon cancer cell lines. Silencing DANCR by small interfering RNA significantly inhibited cell proliferation and colony formation. apoptosis was induced upon DANCR-knockdown. |
| Pubmed ID | 30127873 |
| Year | 2018 |
| Title | Silencing long non-coding RNA, differentiation antagonizing non-protein coding RNA promotes apoptosis and inhibits tumor growth in colon cancer. |
External Links
| Links for DANCR | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |