Basic Information
| LncRNA/CircRNA Name | AF070632 |
| Synonyms | NA |
| Region | GRCh38_1:111770675-111772033 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | Microarray, qPCR etc. |
| Sample | HCC tissues |
| Expression Pattern | down-regulated |
| Function Description | We noted that LINC01419 was characterized by a significant increase in transcript expression from dysplasia to early HCC. The lncRNA AK021443 was also up-regulated in advanced HCC samples when compared with early HCC. Moreover, expression of LINC01419 and AK021443 was up-regulated in HCC tissues when compared with non-tumor liver tissue. AF070632 expression was down-regulated in HCC and was decreased in advanced HCC when compared with early HCC. These results suggest that LINC01419 may be related to the initiation of HCC, whereas AK021443 and AF070632 may be associated with the progression of HCC. |
| Pubmed ID | 26540467 |
| Year | 2015 |
| Title | Long non-coding RNA expression profiles of hepatitis C virus-related dysplasia and hepatocellular carcinoma. |
External Links
| Links for AF070632 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |