Basic Information
| LncRNA/CircRNA Name | AA174084 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, RIP etc. |
| Sample | gastric cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | Expression levels of AA174084 were down-regulated significantly in 95 of 134 GC tissues (71%) compared with the levels in paired, adjacent, normal tissues. AA174084 levels had significant, negative correlations with age, Borrmann type, and perineural invasion. Plasma AA174084 levels in patients with GC dropped markedly on day 15 after surgery compared with preoperative levels and were associated with invasion and lymphatic metastasis. AA174084 levels in gastric juice from patients with GC were significantly higher than the levels in normal mucosa or in patients with minimal gastritis, gastric ulcers, and atrophic gastritis. The area under ROC was up to 0.848. |
| Pubmed ID | 24986041 |
| Year | 2014 |
| Title | Gastric juice long noncoding RNA used as a tumor marker for screening gastric cancer. |
External Links
| Links for AA174084 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |