Basic Information
LncRNA/CircRNA Name | CTC-297N7.9 |
Synonyms | NA |
Region | GRCh38_17:10741267-10769016 |
Ensemble | NA |
Refseq | NA |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | hepatocellular carcinoma |
ICD-0-3 | C22.0 |
Methods | qRT-PCR |
Sample | Hepatocellular carcinoma cell lines, HepG2, SK-hep-1, Huh-7, and the normal liver epithelium cell line LO2,Hepatocellular carcinoma tissues |
Expression Pattern | down-regulated |
Function Description | The expression of CTC-297N7.9 was downregulated in HCC cell lines and HCC tissues.CTC-297N7.9 expression correlated with serum alpha-fetal protein (AFP), tumor stage, and tumor differentiation. Survival analysis indicated that overall survival (OS) and disease-free survival (DFS) are all positively associated with CTC-297N7.9 expression, especially in patients without viral hepatitis or cirrhosis. |
Pubmed ID | 31674731 |
Year | 2019 |
Title | Low Expression of Long Noncoding RNA CTC-297N7.9 Predicts Poor Prognosis in Patients With Hepatocellular Carcinoma |
External Links
Links for CTC-297N7.9 | GenBank HGNC NONCODE |
Links for hepatocellular carcinoma | OMIM COSMIC |