Basic Information
| LncRNA/CircRNA Name | CRNDE |
| Synonyms | CRNDE, CRNDEP, LINC00180, NCRNA00180, PNAS-108, lincIRX5 |
| Region | GRCh38_16:54845189-54929189 |
| Ensemble | ENSG00000245694 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, in vitro knockdown |
| Sample | glioma tissues, cell lines (D54) |
| Expression Pattern | up-regulated |
| Function Description | We confirm that CRNDE acts as an oncogene that is highly up-regulated in glioma, and high CRNDE expression correlates with poor prognosis in glioma patients. |
| Pubmed ID | 28493025 |
| Year | 2017 |
| Title | CRNDE Expression Positively Correlates with EGFR Activation and Modulates Glioma Cell Growth |
External Links
| Links for CRNDE | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |