Basic Information
| LncRNA/CircRNA Name | CRNDE |
| Synonyms | CRNDE, CRNDEP, LINC00180, NCRNA00180, PNAS-108, lincIRX5 |
| Region | GRCh38_16:54845189-54929189 |
| Ensemble | ENSG00000245694 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | hepatocarcinoma tissues, cell lines (LM3, SMMC-7721, Mhepatocarcinoma97H and Mhepatocarcinoma97L, L-02) |
| Expression Pattern | up-regulated |
| Function Description | The results indicated that the expression levels of both lncRNA CRNDE and LINC01419 in HCC patients group were obviously higher than that in healthy. It was found that CRNDE had high sensitivity and specificity in the diagnosis of HCC.The high expression of lncRNA CRNDE and GBAP1 suggested a poor prognosis. |
| Pubmed ID | 29221168 |
| Year | 2017 |
| Title | Diagnosis, prognosis and bioinformatics analysis of lncRNAs in hepatocellular carcinoma. |
External Links
| Links for CRNDE | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |